Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088591 | 0.91 | NAMPT (0.62) | NAMPTDRD2KDM4EPKMSSTR1 | |
| SCHEMBL31617924 | 0.77 | NAMPT (0.56) | NAMPTDRD2KDM4EPKMCKS1B | |
| SCHEMBL1413406 | 0.76 | NAMPT (0.52) | NAMPTDRD2KDM4EPKMACACB | |
| SCHEMBL15934192 | 0.76 | NAMPT (0.49) | NAMPTDRD2KDM4EPKMACACB | |
| SCHEMBL15936742 | 0.76 | NAMPT (0.47) | NAMPTDRD2KDM4EPKMACACB | |
| SCHEMBL25081005 | 0.73 | NAMPT (0.67) | NAMPTDRD2KDM4EPKMACACB | |
| SCHEMBL15936729 | 0.73 | NAMPT (0.58) | NAMPTKDM4EPKMACKR3 | |
| SCHEMBL2826301 | 0.73 | NAMPT (0.61) | NAMPTDRD2KDM4EPKMACKR3 | |
| SCHEMBL21089019 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL28664533 | 0.72 | ALDH1A1 (0.52) | NAMPTDRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |