SCHEMBL1593738

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2057991	0.91	ALDH1A1 (0.54)	ALDH1A1GAAL3MBTL1SMN1; SMN2HPGD
	SCHEMBL1594041	0.85	ALDH1A1 (0.56)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1594022	0.85	ALDH1A1 (0.56)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1593729	0.84	ALDH1A1 (0.55)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1594564	0.82	ALDH1A1 (0.63)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1594922	0.82	ALDH1A1 (0.63)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1594447	0.81	ALDH1A1 (0.59)	ALDH1A1HDAC6HDAC2HDAC8GAA
	SCHEMBL1594597	0.81	ALDH1A1 (0.54)	ALDH1A1HDAC6HDAC2HDAC8GAA
	SCHEMBL1593975	0.81	ALDH1A1 (0.54)	ALDH1A1AKT3HDAC6HDAC2HDAC8
	SCHEMBL1593809	0.81	ALDH1A1 (0.61)	ALDH1A1AKT3HDAC6HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.