SCHEMBL15937787

SCHEMBL15937787

O=C(O)c1ccc2c(c1)C(C1c3ccccc3-c3ccc(Br)cc31)c1ccccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
MAPK1 P28482 1/20 0.50
SRD5A2 P31213 3/20 0.49
SRD5A1 P18405 2/20 0.49
TTR P02766 1/20 0.46
PTPRC P08575 2/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.43
HTR7 P34969 6/20 0.43
HTR2B P41595 6/20 0.43
EDNRB P24530 1/20 0.43
EDNRA P25101 1/20 0.43
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15937977 0.87 CYP1A2 (0.49) CYP1A2MAPK1SRD5A2SRD5A1PTPRC
SCHEMBL13855743 0.78 ATM (0.52) SRD5A2PTPRCKMT2AMEN1ALDH1A1
SCHEMBL13855345 0.78 ATM (0.52) SRD5A2PTPRCKMT2AMEN1ALDH1A1
SCHEMBL30184247 0.76 HTR2B (0.63) SRD5A2SRD5A1TTRPTPRCKMT2A
SCHEMBL4921360 0.74 KMT2A (0.44) SRD5A2SRD5A1TTRPTPRCKMT2A
SCHEMBL14675599 0.74 CYP1A2 (0.46) CYP1A2MAPK1PTPRCKMT2AGAA
SCHEMBL30571871 0.74 HTR7 (0.62) SRD5A2SRD5A1TTRPTPRCKMT2A
SCHEMBL7825562 0.74 HTR7 (0.62) SRD5A2SRD5A1TTRPTPRCKMT2A
SCHEMBL14124766 0.74 EDNRB (0.50) CYP1A2MAPK1SRD5A2SRD5A1PTPRC
SCHEMBL15937786 0.74 MAPK1 (0.44) CYP1A2MAPK1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780311-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-10-03 US disclosed
US-20140225040-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2014-08-14 US disclosed