SCHEMBL15938281

SCHEMBL15938281

COc1cccc(N2CCN(Cc3ccccc3-c3ccccc3)CC2)c1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 10/20 0.73
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
DRD2 P14416 2/20 0.58
DRD4 P21917 1/20 0.58
DRD3 P35462 1/20 0.58
KCNH2 Q12809 1/20 0.56
MAPT P10636 2/20 0.56
TSHR P16473 1/20 0.56
HTR1A P08908 2/20 0.55
LMNA P02545 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764262 1.00 HTR7 (0.73) HTR7KDM4EALDH1A1SMN1; SMN2DRD2
SCHEMBL15937632 0.90 HTR7 (0.72) HTR7DRD2DRD4DRD3MAPT
SCHEMBL15938040 0.87 HTR7 (0.74) HTR7SMN1; SMN2DRD2DRD4DRD3
SCHEMBL29764208 0.87 HTR7 (0.74) HTR7SMN1; SMN2DRD2DRD4DRD3
SCHEMBL15938028 0.85 HTR7 (1.00) HTR7KDM4EALDH1A1DRD2DRD4
SCHEMBL15938053 0.84 HTR7 (1.00) HTR7KDM4EDRD2DRD4DRD3
SCHEMBL15938148 0.84 HTR7 (1.00) HTR7KDM4EALDH1A1SMN1; SMN2DRD2
SCHEMBL29764254 0.84 HTR7 (1.00) HTR7KDM4EALDH1A1SMN1; SMN2DRD2
SCHEMBL1540640 0.82 HTR7 (0.64) HTR7KDM4EALDH1A1SMN1; SMN2DRD2
SCHEMBL1540642 0.82 HTR7 (0.64) HTR7KDM4EALDH1A1SMN1; SMN2DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710438-B Metal oxide dispersion, thin film composition for display, and optical element for display 凯斯科技股份有限公司 2024-01-30 CN claimed
CN-114656818-B metal oxide dispersion 凯斯科技股份有限公司 2023-11-17 CN claimed
CN-115710438-A Metal oxide dispersion, thin film composition for display, and optical element for display 凯斯科技股份有限公司 2023-02-24 CN claimed
CN-114656818-A Metal oxide dispersion 凯斯科技股份有限公司 2022-06-24 CN claimed
CN-115710438-B Metal oxide dispersion, thin film composition for display, and optical element for display 凯斯科技股份有限公司 2024-01-30 CN disclosed
CN-114656818-B metal oxide dispersion 凯斯科技股份有限公司 2023-11-17 CN disclosed
CN-115710438-A Metal oxide dispersion, thin film composition for display, and optical element for display 凯斯科技股份有限公司 2023-02-24 CN disclosed
CN-114656818-A Metal oxide dispersion 凯斯科技股份有限公司 2022-06-24 CN disclosed
US-8883796-B2 Biphenyl derivatives, pharmaceutical composition comprising the same, and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-11-11 US disclosed
US-20140228568-A1 BIPHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228568-A1 BIPHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND PREPARATION METHOD THEREOF HTR7, HTR6, HTR3B HTR7 1/4885KDM4E 3428/4885ALDH1A1 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.