Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15939401 | 0.92 | ACACB (0.35) | ACACB | |
| SCHEMBL15945104 | 0.91 | ACACB (0.34) | ACACBS1PR1 | |
| SCHEMBL15939479 | 0.87 | FFAR1 (0.36) | ACACB | |
| SCHEMBL15939390 | 0.85 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL15939537 | 0.84 | ALDH1A1 (0.37) | ACACB | |
| SCHEMBL15939638 | 0.77 | POLB (0.38) | ACACB | |
| SCHEMBL15939326 | 0.77 | S1PR1 (0.37) | ACACBS1PR1 | |
| SCHEMBL15939377 | 0.72 | ALDH1A1 (0.38) | ACACB | |
| SCHEMBL15939013 | 0.71 | S1PR1 (0.36) | S1PR1 | |
| SCHEMBL8496037 | 0.71 | S1PR1 (0.52) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014126932-A1 | ALKYNE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| US-20140228445-A1 | ALKYNE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228445-A1 | ALKYNE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | ACACB 1482/4885S1PR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.