Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL27694783 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Myristic Acid SCHEMBL27703921 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Stearic Acid SCHEMBL27760235 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Palmitic Acid SCHEMBL27724441 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Octanoic Acid SCHEMBL27694787 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Heptanoate SCHEMBL27694786 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Stearic Acid SCHEMBL11037429 | 0.98 | MEN1 (0.67) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Dodecanoate SCHEMBL3751039 | 0.98 | MEN1 (0.67) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Valeric Acid SCHEMBL27714751 | 0.94 | MEN1 (0.55) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Oleic Acid SCHEMBL27727348 | 0.92 | DGKA (0.70) | MEN1KMT2AKDM4EDUSP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101407-B1 | KIT AND METHOD FOR ELECTRON MICROSCOPE OBSERVATION | JAPAN SCIENCE & TECH AGENCY (JP) | 2023-03-08 | — | — | EP | disclosed |
| US-10128078-B2 | Protective agent for electron microscopic observation of biological sample in water-containing state, kit for electron microscopic observation, methods for observation, diagnosis, evaluation, and quantification by electron microscope, and sample stage | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-2755225-B1 | ELECTRON-MICROSCOPIC EXAMINATION METHOD FOR EXAMINING A LIVING BIOLOGICAL SAMPLE | JAPAN SCIENCE & TECH AGENCY (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-9557253-B2 | Electron microscopic observation method for observing biological sample in shape as it is, and composition for evaporation suppression under vacuum, scanning electron microscope, and transmission electron microscope used in the method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-31 | — | — | US | disclosed |
| EP-3101407-A1 | PROTECTANT FOR ELECTRON MICROSCOPE OBSERVATION OF HYDRATED BIOLOGICAL SAMPLE, KIT FOR ELECTRON MICROSCOPE OBSERVATION, METHOD FOR OBSERVATION, DIAGNOSIS, EVALUATION, OR QUANTIFICATION BY ELECTRON MICROSCOPE, AND SAMPLE STAGE | Japan Science And Technology Agency (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-20160343539-A1 | PROTECTIVE AGENT FOR ELECTRON MICROSCOPIC OBSERVATION OF BIOLOGICAL SAMPLE IN WATER-CONTAINING STATE, KIT FOR ELECTRON MICROSCOPIC OBSERVATION, METHODS FOR OBSERVATION, DIAGNOSIS, EVALUATION, AND QUANTIFICATION BY ELECTRON MICROSCOPE, AND SAMPLE STAGE | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-11-24 | — | — | US | disclosed |
| US-20140227734-A1 | ELECTRON MICROSCOPIC OBSERVATION METHOD FOR OBSERVING BIOLOGICAL SAMPLE IN SHAPE AS IT IS, AND COMPOSITION FOR EVAPORATION SUPPRESSION UNDER VACUUM, SCANNING ELECTRON MICROSCOPE, AND TRANSMISSION ELECTRON MICROSCOPE USED IN THE METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-08-14 | — | — | US | disclosed |
| CN-101738669-B | Cellulose acylate film, process for producing the same, polarizing plate, retardation film, optical compensating film, antireflection film, and liquid-crystal display | FUJI PHOTO FILM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101180351-B | Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same | FUJIFILM CORP. (JP) | 2011-11-30 | — | — | CN | disclosed |
| CN-101208189-B | Cellulose acylate film, method for producing same, and use of same | FUJI PHOTO FILM CO LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101090929-B | Cellulose acylate film and method for producing same | FUJI FILM CORP | 2010-11-10 | — | — | CN | disclosed |
| CN-101090928-B | Cellulose acylate film | FUJI PHOTO FILM CO LTD | 2010-06-30 | — | — | CN | disclosed |
| CN-101738669-A | Cellulose acylate film, process for producing the same, polarizing plate, retardation film, optical compensating film, antireflection film, and liquid-crystal display | FUJIFILM CORP | 2010-06-16 | — | — | CN | disclosed |
| CN-101208189-A | Cellulose acylate film and method for producing same, polarizing plate, retardation film, optical compensation film, antireflection film, and liquid crystal display device | FUJIFILM CORP (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101180351-A | Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same | FUJI FILM CORP (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-101090929-A | Cellulose acylate film and method for producing same | FUJI FILM CORP (JP) | 2007-12-19 | — | — | CN | disclosed |
| CN-101090928-A | Cellulose acylate film | FUJIFILM HOLDINGS CORP (JP) | 2007-12-19 | — | — | CN | disclosed |