Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Valeric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL27724441 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Myristic Acid SCHEMBL27703921 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Stearic Acid SCHEMBL27760235 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Heptanoate SCHEMBL27694786 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Dodecanoate SCHEMBL27694783 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Octanoic Acid SCHEMBL27694787 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Stearic Acid SCHEMBL15939441 | 0.94 | MEN1 (0.65) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Stearic Acid SCHEMBL11037429 | 0.92 | MEN1 (0.67) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Dodecanoate SCHEMBL3751039 | 0.92 | MEN1 (0.67) | MEN1KMT2AKDM4EDUSP3LMNA | |
| Succinic Acid SCHEMBL27929020 | 0.86 | LMNA (0.47) | MEN1KMT2AKDM4EDUSP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101738669-B | Cellulose acylate film, process for producing the same, polarizing plate, retardation film, optical compensating film, antireflection film, and liquid-crystal display | FUJI PHOTO FILM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101180351-B | Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same | FUJIFILM CORP. (JP) | 2011-11-30 | — | — | CN | disclosed |
| CN-101208189-B | Cellulose acylate film, method for producing same, and use of same | FUJI PHOTO FILM CO LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101090929-B | Cellulose acylate film and method for producing same | FUJI FILM CORP | 2010-11-10 | — | — | CN | disclosed |
| CN-101090928-B | Cellulose acylate film | FUJI PHOTO FILM CO LTD | 2010-06-30 | — | — | CN | disclosed |
| CN-101738669-A | Cellulose acylate film, process for producing the same, polarizing plate, retardation film, optical compensating film, antireflection film, and liquid-crystal display | FUJIFILM CORP | 2010-06-16 | — | — | CN | disclosed |
| CN-101208189-A | Cellulose acylate film and method for producing same, polarizing plate, retardation film, optical compensation film, antireflection film, and liquid crystal display device | FUJIFILM CORP (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101180351-A | Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same | FUJI FILM CORP (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-101090928-A | Cellulose acylate film | FUJIFILM HOLDINGS CORP (JP) | 2007-12-19 | — | — | CN | disclosed |
| CN-101090929-A | Cellulose acylate film and method for producing same | FUJI FILM CORP (JP) | 2007-12-19 | — | — | CN | disclosed |