SCHEMBL1594029

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1593816	0.90	HDAC4 (0.53)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1593436	0.88	PDK2 (0.47)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL5597962	0.86	HDAC6 (0.54)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1593804	0.83	ALDH1A1 (0.62)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL14412179	0.82	HDAC4 (0.44)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1594147	0.81	ALDH1A1 (0.48)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL9966092	0.81	HDAC4 (0.45)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1594451	0.78	ALDH1A1 (0.72)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1594601	0.78	HDAC4 (0.52)	HDAC4HDAC6HDAC3HDAC1HDAC7
	SCHEMBL1594551	0.75	EPHX2 (0.46)	HDAC4ALDH1A1PDK2RARGRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.