Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 16/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868773 | 0.89 | EIF2AK3 (0.69) | EIF2AK3MAPK1RIPK1EIF2AK2 | |
| SCHEMBL868994 | 0.87 | EIF2AK3 (0.73) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL868645 | 0.83 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869888 | 0.83 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869091 | 0.83 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869218 | 0.82 | EIF2AK3 (0.72) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869039 | 0.81 | EIF2AK3 (0.68) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL30361395 | 0.80 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869562 | 0.80 | EIF2AK3 (1.00) | EIF2AK3MAPK1RIPK1 | |
| SCHEMBL869204 | 0.80 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227289-A1 | COMPOUNDS AND METHODS FOR TREATING INSULIN RESISTANCE SYNDROME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-08-14 | — | — | US | claimed |