SCHEMBL15940331

SCHEMBL15940331

Nc1ccc2ccccc2c1-c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.50
CYP3A4 P08684 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
HPGD P15428 2/20 0.50
CYP2C19 P33261 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KEAP1 Q14145 1/20 0.47
ADORA2A P29274 1/20 0.44
CYP2C9 P11712 1/20 0.42
CES1 P23141 1/20 0.41
CYP1A1 P04798 2/20 0.41
CYP1B1 Q16678 2/20 0.41
XDH P47989 1/20 0.41
GPR84 Q9NQS5 1/20 0.40
HPRT1 P00492 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11066558 0.90 ALDH1A1 (0.50) CYP1A2CYP3A4L3MBTL1HPGDCYP2C19
SCHEMBL31195785 0.84 ALDH1A1 (0.48) CYP3A4L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL188682 0.84 ALDH1A1 (0.48) CYP3A4L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL27846190 0.81 ESR1 (0.46) CYP1A2CYP3A4L3MBTL1HPGDALDH1A1
SCHEMBL14134222 0.81 CYP1A2 (0.48) CYP1A2CYP3A4L3MBTL1HPGDCYP2C19
SCHEMBL30356330 0.81 CYP1A2 (0.48) CYP1A2CYP3A4L3MBTL1HPGDCYP2C19
SCHEMBL30562860 0.81 CA1 (0.44) CYP1A2CYP3A4HPGDCYP2C19ALDH1A1
SCHEMBL29418178 0.80 ALDH1A1 (0.56) CYP1A2CYP3A4HPGDALDH1A1TSHR
SCHEMBL455943 0.80 ALDH1A1 (0.56) CYP1A2CYP3A4HPGDALDH1A1TSHR
SCHEMBL24432375 0.79 IKBKB (0.46) CYP1A2CYP3A4HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9397300-B2 Compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-19 US disclosed
US-20140225070-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-14 US disclosed