SCHEMBL455943

SCHEMBL455943

Nc1ccc2ccccc2c1-c1c(N)ccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 4/20 0.56
TSHR P16473 3/20 0.56
HPGD P15428 2/20 0.56
CYP3A4 P08684 1/20 0.56
KEAP1 Q14145 1/20 0.56
CYP2A6 P11509 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
HPRT1 P00492 2/20 0.52
MAPT P10636 1/20 0.46
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
WDR5 P61964 1/20 0.45
DNMT1 P26358 1/20 0.43
F12 P00748 1/20 0.43
PLAU P00749 1/20 0.43
NCF1 P14598 1/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418178 1.00 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL31633515 0.97 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL31633516 0.97 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Hydrochloric Acid SCHEMBL31439257 0.97 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL13177764 0.89 HPRT1 (0.48) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL11066558 0.88 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL2068058 0.87 PTPN22 (0.52) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL29364830 0.87 PTPN22 (0.52) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL4423942 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL188682 0.86 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798990-A Resin composition and use thereof 苏州生益科技有限公司 2025-04-11 CN claimed
CN-119192573-A Modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-12-27 CN claimed
US-12110390-B2 Solid dispersion, preparation method therefor, chain-extended polyurethane using same, and epoxy resin composition comprising same SAMYANG CORPORATION (KR) 2024-10-08 US claimed
CN-118255991-A Preparation method of light response liquid crystal elastomer metamaterial based on binaphthyl azobenzene monomer 东南大学 2024-06-28 CN claimed
CN-118221342-A Ultralow-loss temperature-resistant optical fiber and preparation method thereof 中天科技光纤有限公司 2024-06-21 CN claimed
CN-118126367-A Preparation method and application of chiral flexible conductive nano film with controllable thickness 吉林大学 2024-06-04 CN claimed
CN-117736579-A Preparation method and application of resin composition 常熟生益科技有限公司 2024-03-22 CN claimed
CN-114276649-B Thermosetting resin composition, preparation method and application thereof 广东盈骅新材料科技有限公司 2024-03-01 CN claimed
CN-116651234-B Chiral binaphthyl polyimide film and preparation method thereof 中国海洋大学 2024-01-23 CN claimed
CN-116970169-A Amine compound modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2023-10-31 CN claimed
US-20030161605-A1 Nonlinear optical chiral compounds and devices incorporating same KVH INDUSTRIES, INC. 2003-08-28 US claimed
WO-2003003112-A1 NONLINEAR OPTICAL CHIRAL COMPOUNDS AND DEVICES INCORPORATING SAME KVH INDUSTRIES, INC. (US) 2003-01-09 WO claimed
EP-1153953-A1 POLYMERIZATION CATALYST FOR POLYESTER PRODUCTION, POLYESTER, AND PROCESS FOR PRODUCING POLYESTER Toyo Boseki Kabushiki Kaisha (JP) 2001-11-14 EP claimed
US-20010039354-A1 Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-08 US claimed
EP-1134226-A2 Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex Takasago International Corporation (JP) 2001-09-19 EP claimed
US-5919981-A USING HYDROGENATION 1,1*-BINAPHTHYL-2,2*-DIAMINE AS CHEMICAL INTERMEDIATE THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 1999-07-06 US claimed
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP claimed
EP-0258967-B2 Process for producing optically active alcohols TAKASAGO PERFUMERY CO LTD (JP) 1996-08-21 EP claimed
US-5395962-A Optical resolution method KANKYO KAGAKU CENTER CO., LTD. (JP) 1995-03-07 US claimed
EP-0258967-A2 Process for producing optically active alcohols Takasago Perfumery Co., Ltd. (JP) 1988-03-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010039354-A1 Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex DRD4, PNMT, DRD1 ALDH1A1 1040/4885HSD17B10 4786/4885TSHR 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.