SCHEMBL15940431

SCHEMBL15940431

O=C(O)C#CN1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23045146 0.71 DDAH1 (0.33)
SCHEMBL6001759 0.69
SCHEMBL12633322 0.67
SCHEMBL4248234 0.66 PTPN7 (0.40) SMN1; SMN2
Propiolic Acid SCHEMBL28157704 0.62 CA12 (0.32) CA12CA1CA9
SCHEMBL592247 0.60
SCHEMBL317539 0.60 CA12 (0.38) CA12CA1CA9RAB9ASMN1; SMN2
Bicarbonate SCHEMBL6150295 0.60 CA1 (0.38) CA12CA1CA9RAB9ASMN1; SMN2
Bicarbonate SCHEMBL14917 0.60 CA1 (0.38) CA12CA1CA9RAB9ASMN1; SMN2
SCHEMBL4200 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111093707-A Tubulysin homolog conjugates containing branched linkers 杭州多禧生物科技有限公司 2020-05-01 CN disclosed
WO-2014121383-A1 A PROCESS FOR THE PREPARATION OF RUFINAMIDE AND INTERMEDIATES THEREOF APOTEX TECHNOLOGIES INC. (CA) 2014-08-14 WO disclosed