Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244810 | 0.85 | P2RX3 (0.39) | P2RX3P2RX2 | |
| SCHEMBL357241 | 0.82 | NR1I2 (0.38) | P2RX3P2RX2 | |
| SCHEMBL357773 | 0.80 | ALDH1A1 (0.39) | P2RX3P2RX2 | |
| SCHEMBL2269597 | 0.79 | P2RX3 (0.42) | P2RX3P2RX2 | |
| SCHEMBL4051058 | 0.77 | P2RX3 (0.46) | P2RX3P2RX2 | |
| SCHEMBL12200045 | 0.77 | P2RX3 (0.40) | P2RX3P2RX2 | |
| SCHEMBL4316321 | 0.77 | P2RX3 (0.60) | P2RX3P2RX2 | |
| SCHEMBL4323150 | 0.77 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL4321379 | 0.77 | NR1I2 (0.54) | P2RX3P2RX2 | |
| SCHEMBL4565089 | 0.77 | NR1I2 (0.36) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570407-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDE DERIVATIVES AND THEIR USE AS P2X3 AND/OR P2X2/3 PURINERGIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-08-13 | — | — | EP | disclosed |