Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15393693 | 0.85 | HTR2C (0.37) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL15763556 | 0.82 | HTR2C (0.41) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL15943752 | 0.73 | HTR2A (0.44) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL15943750 | 0.69 | KDM1A (0.47) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL15372957 | 0.64 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL8329871 | 0.64 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL12039130 | 0.63 | KDM1A (0.40) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL4377576 | 0.61 | KDM1A (0.56) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL9945850 | 0.61 | HTR2C (0.46) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL9945849 | 0.61 | HTR2C (0.42) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164324-B1 | THERAPEUTIC COMPOUNDS | UNIV FLORIDA (US) | 2014-08-13 | — | — | EP | disclosed |