Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945851 | 0.85 | HTR2C (0.40) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL9947168 | 0.82 | HTR2C (0.45) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL15943751 | 0.73 | KDM1A (0.41) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL15943750 | 0.71 | KDM1A (0.47) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL15372957 | 0.69 | KDM1A (0.66) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL8329871 | 0.69 | KDM1A (0.66) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL21311657 | 0.66 | HTR2A (0.50) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL9945850 | 0.66 | HTR2C (0.46) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL9945849 | 0.66 | HTR2C (0.42) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL12039130 | 0.65 | KDM1A (0.40) | HTR2AHTR2CHTR2BHRH3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164324-B1 | THERAPEUTIC COMPOUNDS | UNIV FLORIDA (US) | 2014-08-13 | — | — | EP | disclosed |