Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094830 | 1.00 | TP53 (0.41) | TP53BCHEMAOBCALM1ALDH1A1 | |
| SCHEMBL30129128 | 0.85 | EPHX2 (0.36) | TP53BCHEMAOBALDH1A1CYP1A2 | |
| SCHEMBL11818883 | 0.84 | TP53 (0.38) | TP53BCHEMAOBCALM1ALDH1A1 | |
| SCHEMBL29185757 | 0.82 | EPHX2 (0.38) | TP53BCHEMAOBALDH1A1 | |
| SCHEMBL30151585 | 0.82 | EPHX2 (0.38) | TP53BCHEMAOBALDH1A1 | |
| SCHEMBL30128945 | 0.82 | EPHX2 (0.38) | TP53BCHEMAOBALDH1A1 | |
| SCHEMBL29094817 | 0.81 | SMN1; SMN2 (0.36) | TP53BCHEMEN1KMT2A | |
| SCHEMBL27507506 | 0.81 | MAOB (0.46) | TP53BCHEMAOBCALM1ALDH1A1 | |
| SCHEMBL29094791 | 0.79 | TAAR1 (0.35) | TP53BCHECYP2D6MEN1KMT2A | |
| SCHEMBL13624829 | 0.78 | LOXL2 (0.39) | TP53BCHEMAOBCALM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321722-B2 | Bis-indolic derivatives, their uses in particular as antibacterials | UNIVERSITE JOSEPH FOURIER (FR) | 2016-04-26 | — | — | US | disclosed |
| US-20140228359-A1 | BIS-INDOLIC DERIVATIVES, THEIR USES IN PARTICULAR AS ANTIBACTERIALS | UNIVERSITE JOSEPH FOURIER (FR) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228359-A1 | BIS-INDOLIC DERIVATIVES, THEIR USES IN PARTICULAR AS ANTIBACTERIALS | IDO1, IDO2, AANAT | TP53 3639/4885BCHE 608/4885MAOB 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.