Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 14/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318107 | 0.82 | ACHE (0.42) | TSHRACHEDPP7EPHX1MMP8 | |
| SCHEMBL27991817 | 0.79 | FNTA (0.49) | ACHEDPP7EPHX1MMP8 | |
| SCHEMBL12527171 | 0.77 | ACHE (0.44) | TSHRACHEDPP7EPHX1MMP8 | |
| SCHEMBL10769236 | 0.76 | EPHX1 (0.61) | DPP7EPHX1MMP8 | |
| SCHEMBL11371693 | 0.76 | TSHR (0.48) | TSHRDPP7EPHX1MMP8 | |
| SCHEMBL224484 | 0.76 | EPHX1 (0.52) | ACHEDPP7EPHX1MMP8 | |
| SCHEMBL20987593 | 0.76 | EGLN1 (0.53) | MMP8 | |
| SCHEMBL4427947 | 0.75 | ALDH1A1 (0.34) | TSHRMMP8 | |
| SCHEMBL8815679 | 0.74 | MEN1 (0.55) | ACHEDPP7EPHX1MMP8 | |
| SCHEMBL8374607 | 0.74 | EPHX1 (0.50) | ACHEDPP7EPHX1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056817-B2 | Arylated β-dicarbonyl compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-16 | — | — | US | disclosed |
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | CYP51A1, DDT, CYP3A4 | TSHR 4210/4885ACHE 748/4885DPP7 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.