SCHEMBL15946231

SCHEMBL15946231

O=COc1ccc(C2(c3ccc(C(=O)O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
OPRK1 P41145 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SRD5A2 P31213 5/20 0.40
PDK2 Q15119 2/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
PIM1 P11309 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
RARB P10826 1/20 0.36
RARG P13631 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707487 0.85 SRD5A2 (0.56) PKMGAAKMT2AMEN1POLB
SCHEMBL31147115 0.85 SRD5A2 (0.56) PKMGAAKMT2AMEN1POLB
SCHEMBL30934486 0.85 GAA (0.58) PKMGAAKMT2AMEN1POLB
SCHEMBL29995499 0.85 GAA (0.58) PKMGAAKMT2AMEN1POLB
SCHEMBL5667740 0.85 GAA (0.58) PKMGAAKMT2AMEN1POLB
SCHEMBL20010306 0.83 GAA (0.57) PKMGAAKMT2AMEN1POLB
SCHEMBL21900401 0.81 MAPT (0.45) GAAKMT2AMEN1POLBMAPT
SCHEMBL25933668 0.80 MEN1 (0.41) GAAKMT2AMEN1POLBMAPT
SCHEMBL15127541 0.78 PKM (0.44) PKMGAAKMT2AMEN1POLB
SCHEMBL15127228 0.78 MEN1 (0.40) KMT2AMEN1POLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9156008-B2 Cardo copolybenzimidazoles, gas separation membranes and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-10-13 US disclosed
US-20140224124-A1 CARDO COPOLYBENZIMIDAZOLES, GAS SEPARATION MEMBRANES AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-14 US disclosed