SCHEMBL15946290

SCHEMBL15946290

c1ccc2c(c1)-c1cc3c4ccccc4n(-c4cccc5c4oc4ccccc45)c3cc1C21c2ccccc2-c2cc3c4ccccc4n(-c4cccc5c4oc4ccccc45)c3cc21

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
GGPS1 O95749 1/20 0.34
PRKDC P78527 5/20 0.33
ATM Q13315 1/20 0.32
MEN1 O00255 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16373496 0.95 ALOX5 (0.36) ALOX5GGPS1PRKDCATMMEN1
SCHEMBL14822423 0.94 ALOX5 (0.34) ALOX5GGPS1PRKDCATMMEN1
SCHEMBL24380055 0.91 ALOX5 (0.31) ALOX5
SCHEMBL22617645 0.90 ALDH1A1 (0.31) ALOX5
SCHEMBL14822607 0.89 ALOX5 (0.35) ALOX5GGPS1PRKDCATMMEN1
SCHEMBL20633785 0.86 ALOX5 (0.33) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL21264446 0.85 ALOX5 (0.33) ALOX5GGPS1PRKDC
SCHEMBL15462305 0.84 ALOX5 (0.35) ALOX5GGPS1PRKDCATMMEN1
SCHEMBL23022832 0.84 ALOX5 (0.40) ALOX5GGPS1PRKDCATMMEN1
SCHEMBL25965909 0.84 ALOX5 (0.36) ALOX5GGPS1PRKDCATMPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed