Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946301 | 0.99 | KDM4E (0.38) | KDM4EATML3MBTL1TSPOPDE10A | |
| SCHEMBL14822512 | 0.98 | KDM4E (0.37) | KDM4EATML3MBTL1TSPOPDE10A | |
| SCHEMBL10001475 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1TSPOPDE10A | |
| SCHEMBL16283009 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1TSPOPDE10A | |
| SCHEMBL14822517 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1TSPOPDE10A | |
| SCHEMBL23058895 | 0.97 | ATM (0.38) | KDM4EATML3MBTL1PDE10APGR | |
| SCHEMBL12292011 | 0.97 | ATM (0.38) | KDM4EATML3MBTL1PDE10APGR | |
| SCHEMBL12455986 | 0.97 | PGR (0.33) | ATMPDE10APGRPDK2HSD11B1 | |
| SCHEMBL12181740 | 0.97 | PGR (0.33) | ATMPDE10APGRPDK2HSD11B1 | |
| SCHEMBL15946295 | 0.96 | KDM4E (0.37) | KDM4EATML3MBTL1TSPOPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |