SCHEMBL15946306

SCHEMBL15946306

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5c(c4)c4cc6c(cc4n5-c4ccccc4)C4(c5ccccc5-c5ccccc54)c4ccccc4-6)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
PTGER4 P35408 1/20 0.32
TSPO P30536 1/20 0.31
HDAC4 P56524 1/20 0.31
KMT2A Q03164 2/20 0.31
IL1R1 P14778 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19196069 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL14822510 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL16641306 0.96 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL19196568 0.94 KDM4E (0.41) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL19196016 0.94 KDM4E (0.41) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20007183 0.94 KDM4E (0.43) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL23370631 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL23370420 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL16076404 0.94 KDM4E (0.38) L3MBTL1KDM4EATM
SCHEMBL23370499 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed