SCHEMBL19196016

SCHEMBL19196016

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5c(c4)c4cc6c(cc4n5-c4ccccc4)C(c4ccccc4)(c4ccccc4)c4ccccc4-6)cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19196568 1.00 KDM4E (0.41) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL30266108 0.98 KDM4E (0.43) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL16641300 0.98 KDM4E (0.43) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL19653297 0.97 KDM4E (0.42) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL18623568 0.95 KDM4E (0.41) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL19652674 0.94 KDM4E (0.40) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL19652707 0.94 KDM4E (0.40) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL16076403 0.94 KDM4E (0.36) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL15946306 0.94 L3MBTL1 (0.44) KDM4EATML3MBTL1MEN1MAPT
SCHEMBL19196069 0.94 L3MBTL1 (0.44) KDM4EATML3MBTL1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170222160-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-08-03 US disclosed
US-20170222160-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170222160-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME ALDH1A2, LAGE3, AOX1 KDM4E 1340/4885ATM 4310/4885L3MBTL1 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.