Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283003 | 0.98 | KDM4E (0.43) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL14822424 | 0.95 | PLA2G2A (0.39) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL19652740 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL19653466 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL16283002 | 0.94 | KDM4E (0.42) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL19652914 | 0.94 | KDM4E (0.42) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL19652807 | 0.94 | KDM4E (0.42) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL19830537 | 0.94 | KDM4E (0.44) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL24675447 | 0.94 | KDM4E (0.42) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A | |
| SCHEMBL24676190 | 0.94 | KDM4E (0.42) | KDM4EL3MBTL1ATMPLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| EP-2758372-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |