SCHEMBL16283003

SCHEMBL16283003

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccc3c(c2)c2ccccc2n3-c2ccccc2)oc2ccccc24)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
AHR P35869 2/20 0.35
TSPO P30536 1/20 0.35
HDAC4 P56524 1/20 0.35
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
PLA2G10 O15496 1/20 0.33
MAOA P21397 1/20 0.33
PTPN1 P18031 1/20 0.33
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15946321 0.98 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19652740 0.98 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL14822424 0.98 PLA2G2A (0.39) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19653466 0.98 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL16283002 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19652914 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19652807 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19830537 0.96 KDM4E (0.44) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL24675447 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL24676190 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed