SCHEMBL15946402

SCHEMBL15946402

C1=CC(c2ccccc2)N=N1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.32
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAOA P21397 6/20 0.30
MAOB P27338 6/20 0.30
KDM1A O60341 4/20 0.30
CYP2C19 P33261 4/20 0.30
CYP2B6 P20813 3/20 0.30
CYP1A2 P05177 2/20 0.30
CYP2D6 P10635 2/20 0.30
CYP2C9 P11712 2/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CYP2A6 P11509 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28481462 0.66
SCHEMBL6626970 0.65 RECQL (0.31) RECQLTSHR
SCHEMBL587341 0.62
SCHEMBL20511049 0.62 TSHR (0.31) TSHRMAOAMAOBKDM1ACYP2C19
SCHEMBL18814601 0.62 RECQL (0.32) RECQLTSHRMAOAMAOBKDM1A
SCHEMBL4908324 0.61
SCHEMBL1975100 0.60 RECQL (0.35) RECQLTSHRGAAMAOAMAOB
SCHEMBL18952029 0.59 TSHR (0.31) RECQLTSHR
SCHEMBL4356377 0.58 RECQL (0.42) RECQLTSHRMAOAMAOBKDM1A
SCHEMBL4486696 0.58 TSHR (0.36) TSHRKDM4EGAAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282961-A1 3D-printed products LANXESS DEUTSCHLAND GMBH (DE) 2025-09-11 US disclosed
CN-105198888-A 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone, derivative and synthetic method of 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone and derivative UNIV XIANGTAN 2015-12-30 CN disclosed
US-20140227207-A1 COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN THE PROCTER & GAMBLE COMPANY (US) 2014-08-14 US disclosed
US-20140227207-A1 COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN THE PROCTER & GAMBLE COMPANY (US) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227207-A1 COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN TYR, CUTA, CDKN1A RECQL 1460/4885TSHR 3804/4885KDM4E 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.