Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947311 | 0.82 | KDM4E (0.34) | ALDH1A1HPGD | |
| SCHEMBL15947291 | 0.81 | IRAK4 (0.33) | IRAK4KDM5AKDM4CFFAR4 | |
| SCHEMBL15947268 | 0.79 | XDH (0.46) | KDM5AKDM4C | |
| SCHEMBL15947315 | 0.79 | LDHA (0.41) | — | |
| SCHEMBL4847728 | 0.78 | CYP26A1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL16740890 | 0.78 | TTR (0.46) | KDM5AKDM4CLMNAFFAR4KMT2A | |
| SCHEMBL8939992 | 0.78 | TTR (0.42) | LMNAFFAR4 | |
| SCHEMBL9095594 | 0.77 | GAA (0.37) | IRAK4LMNAALDH1A1HPGDMEN1 | |
| SCHEMBL15947266 | 0.76 | HTR2A (0.36) | IRAK4ALDH1A1HPGDMEN1GAA | |
| SCHEMBL15947310 | 0.75 | MEN1 (0.33) | ALDH1A1HPGDMEN1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121695-A1 | NOVEL XANTHINE OXIDASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 镇江新元素医药科技有限公司 (CN) | 2014-08-14 | — | — | WO | disclosed |