Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853588 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL8404645 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL7776599 | 0.82 | ALDH1A1 (0.84) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL26219802 | 0.81 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL23476689 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL5893917 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL8612141 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL14132270 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL30325135 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL30325179 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227780-A1 | METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-08-14 | — | — | US | disclosed |