Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26219802 | 0.98 | ALDH1A1 (0.82) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL18894208 | 0.92 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL9066249 | 0.90 | ALDH1A1 (0.96) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL8048430 | 0.90 | ALDH1A1 (0.96) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL12169334 | 0.86 | ALDH1A1 (0.87) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL23476689 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAHPGDCA2MAPT | |
| SCHEMBL5893917 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAHPGDCA12CA2 | |
| SCHEMBL29316529 | 0.84 | ALDH1A1 (0.84) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL439077 | 0.84 | ALDH1A1 (0.84) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL16503455 | 0.84 | ALDH1A1 (0.84) | ALDH1A1LMNAHPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321016-A1 | COMBINATION THERAPY FOR TREATING CANCER | GONGWIN BIOPHARM CO., LTD (TW) | 2023-10-12 | — | — | US | disclosed |
| US-11752118-B2 | Method for treating melanoma | GONGWIN BIOPHARM CO., LTD (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11752160-B2 | Method for reducing fat by administering benzenesulfonamide compositions | GONGWIN BIOPHARM CO., LTD (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20220168248-A1 | METHOD FOR TREATING MELANOMA | GONGWIN BIOPHARM CO., LTD (TW) | 2022-06-02 | — | — | US | disclosed |
| US-20200338028-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR MODULATING LIPID RAFT | GONGWIN BIOPHARM CO., LTD. (TW) | 2020-10-29 | — | — | US | disclosed |
| US-10548862-B2 | Topical formulation and method for preventing or treating acne | Wu, Lester J. (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190321313-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR TREATING CANCER | Gongwin Biopharm Holdings Co., Ltd. | 2019-10-24 | — | — | US | disclosed |
| US-20190322650-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-10-24 | — | — | US | disclosed |
| US-20190201356-A1 | TOPICAL FORMULATION AND METHOD FOR PREVENTING OR TREATING ACNE | GONGWIN BIOPHARM CO., LTD. (TW) | 2019-07-04 | — | — | US | disclosed |
| US-10338277-B2 | Polarizing plate protective film, polarizing plate, and display | FUJIFILM CORPORATION (JP) | 2019-07-02 | — | — | US | disclosed |
| US-20140206689-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-07-24 | — | — | US | disclosed |
| US-8722704-B2 | Modulators of ATP-binding cassette-transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130296364-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130245010-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2013-09-19 | — | — | US | disclosed |
| US-20130245010-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2013-09-19 | — | — | US | disclosed |
| US-8461156-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-06-11 | — | — | US | disclosed |
| US-8324207-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-04 | — | — | US | disclosed |
| EP-0477912-B1 | Novel N-acyldipeptides, and pharmaceutical compositions containing the same | UNIV LJUBLJANI (SI) | 2001-08-29 | — | — | EP | disclosed |
| US-5514654-A | ANTITUMOR AGENTS AND IMMUNOMODULATORS | UNIV LJUBLJANI (SI) | 1996-05-07 | — | — | US | disclosed |
| EP-0477912-A2 | Novel N-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same | UNIVERZA EDVARDA KARDELJA V LJUBLJANI, VDO FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, N.SOL.O., LUBLJANA (YU) | 1992-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190321313-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR TREATING CANCER | ARSA, ABCB1, ABCG2 | ALDH1A1 689/4885LMNA 3088/4885HPGD 1032/4885 |
| US-20130245010-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 1991/4885LMNA 3485/4885HPGD 1969/4885 |
| US-10548862-B2 | Topical formulation and method for preventing or treating acne | CUTA, STS, ALAD | ALDH1A1 669/4885LMNA 3159/4885HPGD 410/4885 |
| US-20190322650-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 1786/4885LMNA 3535/4885HPGD 1792/4885 |
| US-20130296364-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 1985/4885LMNA 3826/4885HPGD 1862/4885 |
| US-11752160-B2 | Method for reducing fat by administering benzenesulfonamide compositions | LIPE, FABP4, LIPA | ALDH1A1 728/4885LMNA 920/4885HPGD 730/4885 |
| US-20220168248-A1 | METHOD FOR TREATING MELANOMA | TYR, MITF, BRAF | ALDH1A1 528/4885LMNA 2154/4885HPGD 784/4885 |
| US-20230321016-A1 | COMBINATION THERAPY FOR TREATING CANCER | TP53, MCL1, TOP2B | ALDH1A1 381/4885LMNA 2924/4885HPGD 687/4885 |
| US-11752118-B2 | Method for treating melanoma | TYR, MITF, BRAF | ALDH1A1 528/4885LMNA 2154/4885HPGD 784/4885 |
| US-20140206689-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 1786/4885LMNA 3535/4885HPGD 1792/4885 |
| US-20200338028-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR MODULATING LIPID RAFT | ABCB4, SPTSSB, SMPD2 | ALDH1A1 1604/4885LMNA 772/4885HPGD 1633/4885 |
| US-20190201356-A1 | TOPICAL FORMULATION AND METHOD FOR PREVENTING OR TREATING ACNE | CUTA, STS, ALAD | ALDH1A1 669/4885LMNA 3159/4885HPGD 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.