Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404650 | 0.87 | LMNA (0.70) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL14853572 | 0.85 | LMNA (0.64) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL14393413 | 0.85 | HPGD (0.69) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL4064273 | 0.84 | LMNA (0.70) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL506163 | 0.84 | LMNA (0.70) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL13102332 | 0.84 | RAB9A (0.74) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL30287914 | 0.84 | RAB9A (0.74) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL20672120 | 0.84 | LMNA (0.65) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL8245543 | 0.84 | LMNA (0.65) | LMNANPC1POLBRAB9AKMT2A | |
| SCHEMBL166484 | 0.84 | LMNA (0.82) | LMNANPC1POLBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227780-A1 | METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-08-14 | — | — | US | disclosed |