Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334692 | 0.92 | GLA (0.39) | TAS1R3TAS1R1ALOX5CES2CES1 | |
| SCHEMBL439568 | 0.92 | TAS1R3 (0.36) | TAS1R3TAS1R1ALOX5CES2CES1 | |
| SCHEMBL20387064 | 0.91 | GLA (0.35) | TAS1R3TAS1R1ALOX5KMT2ANPC1 | |
| SCHEMBL28061556 | 0.89 | HDAC1 (0.37) | TAS1R3TAS1R1ALOX5GAAHTT | |
| SCHEMBL25440569 | 0.84 | HDAC1 (0.39) | ALOX5KMT2AMAPTCYP1A2GAA | |
| SCHEMBL20091321 | 0.84 | HDAC1 (0.39) | ALOX5KMT2AMAPTCYP1A2GAA | |
| SCHEMBL5554713 | 0.84 | HDAC1 (0.39) | ALOX5KMT2AMAPTCYP1A2GAA | |
| SCHEMBL20689617 | 0.84 | HDAC1 (0.39) | ALOX5KMT2AMAPTCYP1A2GAA | |
| SCHEMBL20372967 | 0.84 | GLA (0.39) | ALOX5HTT | |
| SCHEMBL5903025 | 0.84 | HDAC1 (0.39) | ALOX5KMT2AMAPTCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725787-B1 | PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS | REGENACY PHARMACEUTICALS INC (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-3725787-A1 | PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS | Regenacy Pharmaceuticals, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-2612376-B1 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | FLEXTERRA INC (US) | 2018-11-21 | — | — | EP | disclosed |
| US-8598575-B2 | Semiconducting compounds and related compositions and devices | POLYERA CORPORATION (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2612376-A2 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | Polyera Corporation (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130168659-A1 | Semiconducting Compounds and Related Compositions and Devices | POLYERA CORPORATION (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2012030662-A2 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | POLYERA CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130168659-A1 | Semiconducting Compounds and Related Compositions and Devices | NES, TST, SLC19A2 | TAS1R3 1751/4885TAS1R1 2091/4885ALOX5 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.