Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367136 | 0.94 | MEN1 (0.64) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL9248196 | 0.88 | MEN1 (0.65) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL10211748 | 0.88 | RAB9A (0.57) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL9002108 | 0.85 | SCN1A (0.56) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL1926317 | 0.85 | MEN1 (0.65) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL4453290 | 0.85 | MEN1 (0.69) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL1786140 | 0.85 | MEN1 (0.69) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL60478 | 0.83 | MEN1 (0.63) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL14720174 | 0.83 | MEN1 (0.63) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL31139240 | 0.83 | MEN1 (0.63) | MEN1KMT2ACHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031768-A1 | C-HALOGEN BOND FORMATION | NATIONAL SCIENCE FOUNDATION | 2015-01-29 | — | — | US | disclosed |
| US-20140249329-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-09-04 | — | — | US | disclosed |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | MEN1 3495/4885KMT2A 2849/4885CHRNA7 4395/4885 |
| US-20140249329-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | MEN1 3495/4885KMT2A 2849/4885CHRNA7 4395/4885 |
| US-20150031768-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | MEN1 3495/4885KMT2A 2849/4885CHRNA7 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.