Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | UTRN | P46939 | 3/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933541 | 0.91 | UTRN (0.42) | DDR1ALDH1A1HSPD1PTPN2PTPN1 | |
| SCHEMBL29431584 | 0.91 | UTRN (0.42) | DDR1ALDH1A1HSPD1PTPN2PTPN1 | |
| SCHEMBL17342178 | 0.85 | UTRN (0.41) | ALDH1A1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL15933392 | 0.83 | UTRN (0.42) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL29431585 | 0.83 | UTRN (0.42) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL29431583 | 0.83 | DDR1 (0.36) | DDR1SMN1; SMN2S1PR1 | |
| SCHEMBL15933389 | 0.83 | DDR1 (0.36) | DDR1SMN1; SMN2S1PR1 | |
| SCHEMBL15947491 | 0.82 | PTPN2 (0.39) | ALDH1A1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL15947462 | 0.79 | ALDH1A1 (0.38) | DDR1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL15846770 | 0.79 | UTRN (0.47) | ALDH1A1NPC1TP53PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955178-A1 | CONDENSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-12-16 | — | — | EP | disclosed |
| WO-2014123205-A1 | CONDENSED HETEROCYCLIC COMPOUND | 住友化学株式会社 (JP) | 2014-08-14 | — | — | WO | disclosed |