SCHEMBL17342178

SCHEMBL17342178

CCS(=O)(=O)c1cccnc1-c1nc2cc(C(C)(F)F)ccc2o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UTRN P46939 5/20 0.41
HDAC6 Q9UBN7 2/20 0.41
CYP1A2 P05177 1/20 0.41
AHR P35869 1/20 0.41
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
PTPN2 P17706 4/20 0.37
PTPN1 P18031 4/20 0.37
PTPN5 P54829 4/20 0.37
HSPD1 P10809 1/20 0.36
HSPE1 P61604 1/20 0.36
CETP P11597 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15933541 0.94 UTRN (0.42) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL29431584 0.94 UTRN (0.42) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL29431585 0.92 UTRN (0.42) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL15933392 0.92 UTRN (0.42) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL15846770 0.85 UTRN (0.47) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL15947463 0.85 DDR1 (0.42) UTRNPTPN2PTPN1PTPN5HSPD1
SCHEMBL17342180 0.85 SGMS2 (0.34) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL20582906 0.84 UTRN (0.50) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL15847091 0.84 UTRN (0.39) UTRNHDAC6CYP1A2AHRMEN1
SCHEMBL28499907 0.84 UTRN (0.46) UTRNHDAC6CYP1A2AHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-9723835-B2 Pest control composition and method for controlling pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9549559-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-24 US disclosed
US-20150366208-A1 METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 US disclosed
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 US disclosed
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 US disclosed
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS NIT2, CRY1, CNPY2 UTRN 3733/4885HDAC6 1429/4885CYP1A2 71/4885
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS TH, TCOF1, BLVRB UTRN 1134/4885HDAC6 2664/4885CYP1A2 1010/4885
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS PNPO, NAMPT, NNT UTRN 4825/4885HDAC6 1471/4885CYP1A2 217/4885
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST ABAT, PNPO, GABBR1 UTRN 4618/4885HDAC6 3299/4885CYP1A2 770/4885
US-20150366208-A1 METHOD FOR CONTROLLING PESTS BROX, RNGTT, NOS1 UTRN 4222/4885HDAC6 1064/4885CYP1A2 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.