Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19415286 | 1.00 | LMNA (0.49) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL15917739 | 0.86 | GPBAR1 (0.53) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL18513782 | 0.86 | GPBAR1 (0.53) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL12593295 | 0.85 | PTPN1 (0.57) | LMNAGPBAR1PTPN1F3 | |
| SCHEMBL15947465 | 0.85 | PTPN1 (0.57) | LMNAGPBAR1PTPN1F3 | |
| SCHEMBL9108482 | 0.84 | GPBAR1 (0.52) | LMNASMN1; SMN2GPBAR1NT5E | |
| SCHEMBL9109676 | 0.84 | GPBAR1 (0.52) | LMNASMN1; SMN2GPBAR1NT5E | |
| SCHEMBL22251647 | 0.84 | GPBAR1 (0.52) | LMNASMN1; SMN2GPBAR1NT5E | |
| SCHEMBL9108815 | 0.84 | GPBAR1 (0.72) | LMNASMN1; SMN2GPBAR1NT5E | |
| SCHEMBL9110103 | 0.84 | GPBAR1 (0.72) | LMNASMN1; SMN2GPBAR1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014123889-A1 | C-19 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-08-14 | — | — | WO | disclosed |