Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.51 |
| ▸ | USP7 | Q93009 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593295 | 1.00 | PTPN1 (0.57) | PTPN1F3GPBAR1USP7PRKCD | |
| SCHEMBL15947458 | 0.86 | GPBAR1 (0.56) | PTPN1F3GPBAR1PRKCDUSP2 | |
| SCHEMBL15917888 | 0.85 | GPBAR1 (0.62) | PTPN1F3GPBAR1USP2LMNA | |
| SCHEMBL18513850 | 0.85 | RORC (0.58) | PTPN1F3GPBAR1PRKCDUSP2 | |
| SCHEMBL15918172 | 0.85 | GPBAR1 (0.70) | PTPN1GPBAR1USP2LMNAHIF1A | |
| SCHEMBL19415286 | 0.85 | LMNA (0.49) | PTPN1F3GPBAR1LMNA | |
| SCHEMBL15947464 | 0.85 | LMNA (0.49) | PTPN1F3GPBAR1LMNA | |
| SCHEMBL23284128 | 0.84 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL22251684 | 0.84 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL9108438 | 0.84 | GPBAR1 (0.69) | GPBAR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014123889-A1 | C-19 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-08-14 | — | — | WO | disclosed |