SCHEMBL1594837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13061553	0.85	ALDH1A1 (0.53)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL13008427	0.81	ALDH1A1 (0.53)	ALDH1A1GAAPOLBL3MBTL1CHRM2
	SCHEMBL12706575	0.80	ALDH1A1 (0.57)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL1593433	0.79	ALDH1A1 (0.56)	ALDH1A1GAAPOLBL3MBTL1TSHR
	SCHEMBL12728203	0.78	ALDH1A1 (0.53)	ALDH1A1GAAPOLBL3MBTL1GLA
	SCHEMBL1595185	0.76	ALDH1A1 (0.59)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL1593277	0.76	ALDH1A1 (0.59)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL1593274	0.76	ALDH1A1 (0.59)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL1594739	0.75	ALDH1A1 (0.68)	ALDH1A1GAAPOLBL3MBTL1
	SCHEMBL1594066	0.75	ALDH1A1 (0.61)	ALDH1A1GAAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.