Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.47 |
| ▸ | ADK | P55263 | 4/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912603 | 0.90 | PRMT5 (0.48) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL14134801 | 0.90 | PRMT5 (0.48) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL12151806 | 0.89 | ADK (0.47) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL29363011 | 0.89 | ADK (0.55) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL20059237 | 0.89 | ADK (0.47) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL27786173 | 0.86 | ADK (0.48) | PRMT5WDR77ADKDOT1LNPC1 | |
| SCHEMBL12154911 | 0.86 | ADK (0.48) | PRMT5WDR77ADKDOT1LNPC1 | |
| Lodenosine SCHEMBL30998176 | 0.80 | EGFR (0.61) | PRMT5WDR77DOT1L | |
| Lodenosine SCHEMBL22869478 | 0.80 | EGFR (0.61) | PRMT5WDR77DOT1L | |
| Lodenosine SCHEMBL29663669 | 0.80 | EGFR (0.61) | PRMT5WDR77DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |