Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 15/20 | 0.55 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948739 | 0.89 | PRMT5 (0.47) | ADKRAB9APRMT5WDR77DOT1L | |
| SCHEMBL13068771 | 0.88 | ADK (0.61) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL3768787 | 0.88 | ADK (0.61) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL20419264 | 0.88 | ADK (0.61) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL14154378 | 0.87 | ADK (0.60) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL14134780 | 0.84 | ADK (0.53) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL27764443 | 0.84 | ADK (0.53) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL13293931 | 0.82 | ADK (0.53) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL29365865 | 0.82 | ADK (0.50) | ADKHASPINRAB9AMTORPRMT5 | |
| SCHEMBL22912603 | 0.79 | PRMT5 (0.48) | ADKRAB9APRMT5WDR77DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993877-A | Novel carbonate compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-01-28 | — | — | CN | claimed |
| CN-113993877-A | Novel carbonate compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-01-28 | — | — | CN | disclosed |