SCHEMBL15948817

SCHEMBL15948817

O=C(O)C(F)(F)CCCCCC(F)(F)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
FFAR1 O14842 1/20 0.39
CPT2 P23786 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ACLY P53396 1/20 0.38
S1PR2 O95136 1/20 0.38
S1PR4 O95977 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37
ODC1 P11926 2/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ARG1 P05089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25802000 0.88 CES2 (0.67) CES2S1PR2S1PR4S1PR1S1PR3
SCHEMBL28229868 0.88 TSHR (0.55) FFAR1TDP1MEN1KMT2A
SCHEMBL28151371 0.88 CES2 (0.67) CES2S1PR2S1PR4S1PR1S1PR3
SCHEMBL31190476 0.88 CES2 (0.67) CES2S1PR2S1PR4S1PR1S1PR3
SCHEMBL10623101 0.88 CES2 (0.67) CES2S1PR2S1PR4S1PR1S1PR3
SCHEMBL26293737 0.88 CES2 (0.67) CES2S1PR2S1PR4S1PR1S1PR3
SCHEMBL8816746 0.88 CES2 (0.45) CES2FFAR1CPT2TDP1ACLY
Bromide SCHEMBL11536182 0.86 CES2 (0.39) CES2FFAR1CPT2TDP1ACLY
SCHEMBL7416226 0.85 LMNA (0.52) FFAR1TDP1MEN1KMT2A
SCHEMBL8218831 0.85 CES2 (0.63) CES2S1PR2S1PR4S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
EP-2395040-A1 FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM Central Glass Company, Limited (JP) 2011-12-14 EP disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 CES2 2110/4885FFAR1 91/4885CPT2 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.