Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | POLD1 | P28340 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948840 | 0.83 | P2RY2 (0.41) | POLA1P2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL16576111 | 0.72 | POLG (0.36) | P2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL16575823 | 0.70 | P2RY2 (0.34) | SMN1; SMN2POLBPOLA1POLD1P2RY6 | |
| SCHEMBL15948839 | 0.69 | P2RY2 (0.42) | POLA1P2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL17859315 | 0.69 | POLB (0.35) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL16575821 | 0.69 | P2RY2 (0.34) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL16299256 | 0.67 | POLB (0.43) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL25712429 | 0.67 | P2RY2 (0.44) | POLA1P2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL23805468 | 0.66 | TYMP (0.43) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL4816453 | 0.66 | P2RY6 (0.36) | SMN1; SMN2POLBPOLA1POLD1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |