Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370577 | 0.93 | TAAR1 (0.53) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL1331599 | 0.90 | TAAR1 (0.54) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL8820632 | 0.89 | TAAR1 (0.47) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL825460 | 0.88 | TAAR1 (0.51) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL16243873 | 0.88 | TAAR1 (0.44) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL1974427 | 0.87 | TAAR1 (0.46) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL16243647 | 0.85 | TBXAS1 (0.49) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL27938415 | 0.85 | TAAR1 (0.57) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL11936762 | 0.85 | TAAR1 (0.57) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL1331585 | 0.82 | TAAR1 (0.47) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228407-A1 | TETRA-PYRIDINE COMPOUNDS AND COMPOSITION FOR PROTECTING CELLS, TISSUES AND ORGANS AGAINST ISCHEMIA-REPERFUSION INJURY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY, LTD. (IL) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228407-A1 | TETRA-PYRIDINE COMPOUNDS AND COMPOSITION FOR PROTECTING CELLS, TISSUES AND ORGANS AGAINST ISCHEMIA-REPERFUSION INJURY | TNNI3, TXN2, PRDX5 | TAAR1 2022/4885CYP2D6 2879/4885TSHR 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.