Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.53 |
| ▸ | CTSA | P10619 | 4/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949290 | 1.00 | GPBAR1 (0.53) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949216 | 1.00 | GPBAR1 (0.53) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949058 | 0.95 | GPBAR1 (0.53) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949202 | 0.95 | GPBAR1 (0.53) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949257 | 0.95 | GPBAR1 (0.53) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949186 | 0.93 | GPBAR1 (0.51) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949214 | 0.91 | GPBAR1 (0.56) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1390482 | 0.88 | GPBAR1 (0.58) | GPBAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL364010 | 0.88 | GPBAR1 (0.58) | GPBAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL362306 | 0.88 | GPBAR1 (0.58) | GPBAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |