Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.51 |
| ▸ | CTSA | P10619 | 11/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949202 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949216 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949257 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949058 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949290 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949102 | 0.93 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1 | |
| SCHEMBL15949151 | 0.90 | GPBAR1 (0.54) | GPBAR1CTSAFFAR1S1PR1S1PR3 | |
| SCHEMBL1390491 | 0.90 | GPBAR1 (0.54) | GPBAR1CTSAFFAR1S1PR1S1PR3 | |
| SCHEMBL364564 | 0.90 | GPBAR1 (0.54) | GPBAR1CTSAFFAR1S1PR1S1PR3 | |
| SCHEMBL15949214 | 0.89 | GPBAR1 (0.56) | GPBAR1CTSAFFAR1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |