Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.56 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949187 | 0.92 | GPBAR1 (0.51) | GPBAR1CTSAKCNH2KDM5BFFAR1 | |
| SCHEMBL15949235 | 0.91 | GPBAR1 (0.62) | GPBAR1PORCNPRCPKCNH2PSEN1 | |
| SCHEMBL15949251 | 0.91 | GPBAR1 (0.62) | GPBAR1PORCNPRCPKCNH2PSEN1 | |
| SCHEMBL15949198 | 0.91 | GPBAR1 (0.62) | GPBAR1PORCNPRCPKCNH2PSEN1 | |
| SCHEMBL15949257 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 | |
| SCHEMBL15949290 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 | |
| SCHEMBL15949216 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 | |
| SCHEMBL15949102 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 | |
| SCHEMBL15949058 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 | |
| SCHEMBL15949202 | 0.91 | GPBAR1 (0.53) | GPBAR1PRCPCTSAPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |