Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.36 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949214 | 0.92 | GPBAR1 (0.56) | GPBAR1FFAR1CTSAKCNH2KDM5B | |
| SCHEMBL364258 | 0.89 | GPBAR1 (0.61) | GPBAR1FFAR1CTSAAKR1C3AKR1C2 | |
| SCHEMBL1389844 | 0.89 | GPBAR1 (0.61) | GPBAR1FFAR1CTSAAKR1C3AKR1C2 | |
| SCHEMBL1389847 | 0.89 | GPBAR1 (0.61) | GPBAR1FFAR1CTSAAKR1C3AKR1C2 | |
| SCHEMBL15949235 | 0.85 | GPBAR1 (0.62) | GPBAR1FFAR1KCNH2KDM4CKDM5B | |
| SCHEMBL15949198 | 0.85 | GPBAR1 (0.62) | GPBAR1FFAR1KCNH2KDM4CKDM5B | |
| SCHEMBL15949251 | 0.85 | GPBAR1 (0.62) | GPBAR1FFAR1KCNH2KDM4CKDM5B | |
| SCHEMBL15949290 | 0.85 | GPBAR1 (0.53) | GPBAR1FFAR1CTSAKDM5B | |
| SCHEMBL15949102 | 0.85 | GPBAR1 (0.53) | GPBAR1FFAR1CTSAKDM5B | |
| SCHEMBL15949257 | 0.85 | GPBAR1 (0.53) | GPBAR1FFAR1CTSAKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |