Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.49 |
| ▸ | PROKR1 | Q8TCW9 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949324 | 1.00 | GPBAR1 (0.49) | GPBAR1PROKR1F10F2PLAT | |
| SCHEMBL364374 | 0.90 | GPBAR1 (0.51) | GPBAR1PROKR1F10F2PLAT | |
| SCHEMBL1389686 | 0.90 | GPBAR1 (0.51) | GPBAR1PROKR1F10F2PLAT | |
| SCHEMBL1390284 | 0.90 | GPBAR1 (0.51) | GPBAR1PROKR1F10F2PLAT | |
| SCHEMBL15949212 | 0.90 | GPBAR1 (0.62) | GPBAR1ACACB | |
| SCHEMBL362698 | 0.90 | GPBAR1 (0.51) | GPBAR1PROKR1F10F2PLAT | |
| SCHEMBL15949317 | 0.90 | GPBAR1 (0.62) | GPBAR1ACACB | |
| SCHEMBL15949197 | 0.87 | GPBAR1 (0.65) | GPBAR1F10ACACB | |
| SCHEMBL15949262 | 0.87 | GPBAR1 (0.65) | GPBAR1F10ACACB | |
| SCHEMBL15949294 | 0.82 | GPBAR1 (0.59) | GPBAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |