Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 17/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912448 | 0.88 | MGLL (0.51) | MGLLFAAH | |
| SCHEMBL953292 | 0.85 | MGLL (0.47) | MGLLFAAH | |
| SCHEMBL7784149 | 0.85 | MGLL (0.66) | MGLLFAAHSLC6A7 | |
| SCHEMBL15958970 | 0.85 | MGLL (0.51) | MGLLFAAH | |
| SCHEMBL3779972 | 0.84 | MGLL (0.60) | MGLLFAAH | |
| SCHEMBL6840305 | 0.81 | MGLL (0.50) | MGLLFAAH | |
| SCHEMBL915604 | 0.81 | MGLL (0.64) | MGLLFAAHSLC6A7 | |
| SCHEMBL911408 | 0.79 | MGLL (0.69) | MGLLFAAHSLC6A7 | |
| SCHEMBL911279 | 0.79 | MGLL (0.69) | MGLLFAAHSLC6A7 | |
| SCHEMBL699681 | 0.78 | MGLL (0.59) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421823-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-14 | — | — | EP | disclosed |
| EP-2421825-B9 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-20 | — | — | EP | disclosed |
| EP-2421825-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-01-01 | — | — | EP | disclosed |