SCHEMBL15958970

SCHEMBL15958970

O=C(c1nccs1)N1CCN(C2CN(C(=O)c3cccc4c3CCCC4)C2)CC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 19/20 0.51
FAAH O00519 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6840305 0.87 MGLL (0.50) MGLLFAAH
SCHEMBL953292 0.85 MGLL (0.47) MGLLFAAH
SCHEMBL912448 0.85 MGLL (0.51) MGLLFAAH
SCHEMBL15949451 0.85 MGLL (0.54) MGLLFAAH
SCHEMBL913196 0.78 MGLL (0.55) MGLLFAAH
SCHEMBL7784149 0.78 MGLL (0.66) MGLLFAAH
SCHEMBL913307 0.77 MGLL (0.56) MGLLFAAH
SCHEMBL912602 0.77 MGLL (0.57) MGLLFAAH
SCHEMBL911550 0.77 MGLL (0.53) MGLLFAAH
SCHEMBL911511 0.77 MGLL (0.53) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421825-B9 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-20 EP disclosed