Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329762 | 0.73 | TAAR1 (0.42) | TDP1CALM1TAAR1TSHRNPC1 | |
| SCHEMBL30148126 | 0.69 | HTR2A (0.63) | TDP1CALM1BCL2BCL2L1HTR2A | |
| SCHEMBL8871441 | 0.69 | HTR2A (0.63) | TDP1CALM1BCL2BCL2L1HTR2A | |
| SCHEMBL7576190 | 0.67 | IDO1 (0.38) | BCL2L1TAAR1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3884966 | 0.64 | TDP1 (0.80) | TDP1CALM1TAAR1TSHRALDH1A1 | |
| SCHEMBL29076175 | 0.64 | TDP1 (0.56) | TDP1CALM1BCL2BCL2L1TAAR1 | |
| Phenylethyl Alcohol SCHEMBL28162594 | 0.64 | TDP1 (0.89) | TDP1TAAR1HTR2ATSHRALDH1A1 | |
| Phenylethyl Alcohol SCHEMBL11196640 | 0.64 | TDP1 (0.89) | TDP1TAAR1HTR2ATSHRALDH1A1 | |
| SCHEMBL3839140 | 0.64 | TDP1 (0.41) | TDP1BCL2BCL2L1HTR2APAX8 | |
| Phenylethyl Alcohol SCHEMBL11450063 | 0.63 | TDP1 (1.00) | TDP1CALM1TAAR1HTR2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919626-B2 | Pyrazole compounds and uses thereof | HELICON THERAPEUTICS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20070203154-A1 | Therapeutic Compounds | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203154-A1 | Therapeutic Compounds | MAOB, MAOA, HTR1B | TDP1 500/4885CALM1 932/4885BCL2 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.