Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576499 | 0.82 | IKBKB (0.34) | IDO1SMN1; SMN2 | |
| SCHEMBL8473218 | 0.76 | HPGD (0.53) | IDO1ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL7570634 | 0.73 | SMN1; SMN2 (0.40) | IDO1ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL7572110 | 0.69 | KDM1A (0.40) | ALDH1A1HPGDHSD17B10SMN1; SMN2CCNB2 | |
| SCHEMBL1594956 | 0.67 | TDP1 (0.42) | ALDH1A1BCL2L1SMN1; SMN2TSHRTAAR1 | |
| SCHEMBL43837 | 0.65 | TAAR1 (0.62) | IDO1TSHRTAAR1 | |
| SCHEMBL29646276 | 0.65 | TAAR1 (0.62) | IDO1TSHRTAAR1 | |
| SCHEMBL28308651 | 0.65 | TAAR1 (0.62) | IDO1TSHRTAAR1 | |
| SCHEMBL3763076 | 0.65 | PDCD1 (0.38) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| Ethylene Glycol SCHEMBL7109461 | 0.64 | ALDH1A1 (0.62) | IDO1ALDH1A1HPGDBCL2L1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089799-A2 | USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |